Up to 40 percent of travelers worldwide are affected each year by a painful disorder in the digestive tract called traveler’s diarrhea.
The condition, which is defined in 24 hours by having three or more unformed stools, can derail your travel plans and leave you in bedridden with nausea, abdominal cramps, and persistent vomiting.
Now when diarrhea strikes adult travelers have a new treatment option.
Recently, the FDA approved uncomfortable symptoms due to non-invasive Escherichia coli ( E. coli) that do not involve bloody stools or fevers.
The drug, to be taken by mouth, is expected to be available by February, the FDA stated. You can buy generic medication to treat traveler’s diarrhea at safe healths online pharmacy.
The medicine treats specifically diarrhea caused by E. coli
To test Aemcolo’s effectiveness, researchers in Guatemala and Mexico studied 264 adults with traveler’s diarrhea. The clinical trial showed that Aemcolo greatly alleviated diarrhea symptoms in patients as compared with the placebo.
The drug ‘s safety was then tested in 2 randomized clinical trials in 619 adults with traveler’s diarrhea. The most common adverse side effects have been headache and constipation, according to the FDA.
Aemcolo was not effective in those who were experiencing fever and/or bloody stools caused by other than E.Coli.
There are two types of strains: invasive and noninvasive
After eating food or water infected with invasive and non-invasive bacteria, viruses, and parasites, Traveler’s diarrhea usually enters.
According to the Centers for Disease Control and Prevention ( CDC), the most common culprit is bacterial pathogens.
- Coli provokes several assaults. The non-invasive bacteria attach to your intestine ‘s lining, releasing a toxin that triggers diarrhea and cramps.
More invasive bacteria — including jejuni Campylobacter, spp. Shigella, and spp. Salmonella. — causes bloody diarrhea and a high fever.
The CDC states that traveler diarrhea can strike anywhere, but is most common in Asia, the Middle East, Africa, Mexico, and Central and South America. Eastern Europe, South Africa, and several Caribbean islands are also considered places of higher risk.
Treatment varies from case to case
In more acute cases involving serious dehydration, constant vomiting, a high fever, or bloody stools, it is important to seek urgent medical attention. Severe dehydration may be catastrophic, as large quantities of essential fluids, salts, and minerals can be lost.
The two types of drugs used to treat traveler diarrhea fall into two categories: symptomatic relief (think antidiarrheals) and antibiotics — such as azithromycin, ciprofloxacin, rifaximin, and now rifamycin — which can help clear the bacteria and improve healing.
Rifaximin (rifagut) is often prescribed for more serious traveler diarrhea as one of the first-line antibiotic therapies since it contains a larger amount of pathogens.
Rehydration is the mainstay for treating diarrhea
Because some bacteria have become increasingly resistant to antibiotics, some health experts think the discovery and approval of new treatments, such as rifamycin, is extremely valuable.
Others argue that the traveler’s diarrhea caused by E. coli does not even require antibiotics — and if overprescribed or misused, the drug does potentially do more harm than good.
Aemcolo is only approved for the non-invasive E treatment. Coli, a self-limited infection that some say does not even require antibiotic therapy, but rehydration and/or loperamide as the key therapy part, a pediatric infectious disease specialist at the NYU Winthrop Hospital Family Travel Clinic.
“In the travel community, there is growing concern about the misuse of scientific antibiotics and the ‘overtreatment’ of diarrhea that is experienced abroad. For this purpose, antibiotics should only be considered or prescribed in cases of mild or extreme diarrhea, respectively.
Regardless, if you get a traveler’s diarrhea the most important thing to do is concentrate on rehydration, Fiorito explained. This — besides over-the-counter medications such as loperamide — is considered the first line of defense.
Watch what you eat and drink while traveling
Fortunately, by steering clear of the pathogens that trigger it you can significantly reduce your chances of traveler’s diarrhea.
Boil it, fry it, cut it, or forget it when in doubt, as the saying goes. High heat destroys germs, so make a point of consuming cooked and hot food, instead of keeping it at room temperature.
Avoiding high-risk foods treated by individuals but not cooked, such as potatoes, can also be effective in eliminating tap water and then opting for filtered water.
Every case varies: Where one person may need only rehydration therapy, another may benefit from a full antibiotic course. The best course of action for your particular symptoms can be decided by a healthcare provider.
Although traveler’s diarrhea is generally harmless, the difference between successful, safe travel and a trip spent curled up in bed might be the cure for it quickly.